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Our Approach

Parkinson's Plus Syndromes are defined as Secondary and Atypical Parkinsonism. The Neuroscience Institute has found that our patients with this condition do not respond to the standard treatments for Parkinson’s disease, which suggests the syndrome warrants a search for the signs and symptoms of degeneration in other neuronal systems. Our patients suffering from Parkinson-plus syndromes may experience early onset signs of dementia, postural instability, hallucinations or psychosis.


The following syndromes are associated with Parkinson's Plus:

  • Progressive supranuclear palsy (PSP): An uncommon brain disorder that severely affects a patient's mood and behavior, their ability to move, walk, balance, speak, swallow, see, and think.
  • Multiple system atrophy (MSA): A neurodegenerative disorder that affects the autonomic system (the part of your nervous system that involuntary controls blood pressure or digestion) and overall movement.
  • Cortical basilar ganglionic degeneration: A neurological disorder that involves nerve cell loss and atrophy (shrinkage of multiple areas of the brain including the cerebral cortex and the basal ganglia).
  • Frontotemporal dementia with parkinsonism (FTD-17): A clinical syndrome connected with the shrinking of the frontal and anterior lobes of the brain.

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