Leg Pain and Fatigue Causes and Treatment

Leg Pain and Fatigue  

Leg pain and fatigue can follow a hard workout at the gym or sitting too long in a cramped car during a road trip. However, the soreness should fade within a day or two, and your legs should start feeling normal.

But sometimes, leg pain does not go away, which could indicate an underlying health problem. So do not ignore ongoing pain in your legs — your primary care physician can help find and treat the issue and get you back on your feet.

Causes of Leg Pain and Fatigue

Chronic venous insufficiency, a venous disorder, is a significant cause of heaviness and pain in the legs. This condition occurs when veins deep in the legs that keep blood flowing back to the heart weaken, allowing blood to pool.

People who sit or stand for long periods, those who are overweight or obese, and women are at greater risk for this condition, which causes leg pain and fatigue. Leg pain can result from several types of injuries, diseases, lifestyle choices and many other causes.


  • Inflamed tendon
  • Shin splints
  • Strain
  • Stress fracture



  • Dehydration
  • Muscle fatigue after exercise
  • Obesity
  • Poor circulation

Other Causes

  • Blood clots
  • Bone infection
  • Medication side effects
  • Sciatic nerve pain

Diagnosing Leg Pain and Fatigue

There are countless causes for leg pain and fatigue. Seeing your physician is the only way to get an accurate diagnosis. You should contact your physician if you have leg pain accompanied with swelling, fever or discoloration (black or bluish tint to leg). It is also important to see a physician if your leg pain is getting worse and at-home self-care is not helping.

To diagnose leg pain, your physician will start by examining your legs, as well as your feet, back and hips. You will be asked to describe the pain and explain what makes it worse or better. Your physician may order additional tests, such as an X-ray or MRI, to get a more detailed look at your leg.

Leg Pain and Fatigue Treatment

Your physician will address the root cause of leg pain and fatigue to help you find relief. Here are a few treatment options your health care provider may recommend:

  • Compression therapy. This involves wearing supportive socks that apply gentle pressure to control leg swelling and discomfort.
  • Medicine. Nonsteroidal anti-inflammatory medications can help with mild to moderate leg pain. If you are prone to blood clots, your physician may have you take medicine to thin your blood. You may need to take antibiotics if you have an infection.
  • Physical therapy. Completing leg exercises with a supervised physical therapist can ease painful symptoms and restore motion in the joint.
  • Surgery. You may need surgery for varicose veins, severe tendon damage, sprains and strains, or other leg injuries.

Prevent Leg Pain and Fatigue

It is not always possible to prevent leg pain. However, your lifestyle does play a part in reducing your risk. Here are few lifestyle changes to make to prevent leg pain:

  • Aim for a healthy weight.
  • Avoid sitting or standing too long.
  • Eat a heart-healthy diet.
  • Follow your physician’s recommendations for physical activity.
  • Promote leg circulation with exercise, compression stockings and leg elevation.
  • Quit smoking to decrease your risk of PAD and blood clots.
  • Take rest days from exercise.
  • Warm up before exercise (every time, no exceptions).

Find a Primary Care Provider

Find a CHRISTUS Health family doctor or primary care provider in Texas, Louisiana and New Mexico.

Search for a Provider

Learn More

Chronic Inflammation

Diabetes and Inflammation: The Role of Chronic Inflammation

Inflammation has become increasingly linked to the development of chronic diseases, particularly diabetes. Schedule an appointment with a primary doctor to help manage your risk or chronic disease.

Read the latest stories from CHRISTUS Health Experts

What is Uncontrolled Diabetes? | CHRISTUS Health

As one of the leading causes of disability and premature death in the United States, it's essential to understand how to manage diabetes and reduce its impact on your life.

Weight Loss and Obesity

Discover the path to a healthier you. Explore the latest insights, science-backed strategies, and expert tips from CHRISTUS Health to conquer obesity, transform your lifestyle, and achieve your weight loss goals.

Treating Obesity 101

People who live with obesity have higher risks of heart disease, higher risk of mental health issues and are at risk of other health issues like sleep apnea and high blood pressure. Learn more about obesity and why it should be treated.

8 Facts About Bariatric Surgery You Should Know

Dive into the comprehensive approach of bariatric surgery. From a holistic lifestyle change to the impact on chronic conditions, uncover eight fascinating facts about this transformative journey.